Abstract P-479
نویسندگان
چکیده
منابع مشابه
Dmd048561 475..479
This study was designed to evaluate the in vivo activity of cytochrome P450 3A (CYP3A) in 49 healthy Japanese subjects aged 22–58 years using endogenous cortisol 6b-hydroxylation clearance [CLm(6b)], a novel biomarker for CYP3A phenotyping. CLm(6b) in the 49 healthy subjects was 2.40 6 0.79 ml/min with an approximately 4fold interindividual variability of CYP3A activity. The mean clearance in t...
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Microphthalmos is an ocular abnormality of the eye in which all tissues are significantly smaller than normal. It is subdivided into two categories as simple and complex microphthalmos. The complex type is associated with several ocular abnormalities (1). Posterior microphthalmos is another subtype of microphthalmos which is characterized by normal or near normal anterior segment dimensions, ye...
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Motivation: Owing to its importance in both basic research (such as molecular evolution and protein attribute prediction) and practical application (such as timely modeling the 3D structures of proteins targeted for drug development), protein remote homology detection has attracted a great deal of interest. It is intriguing to note that the profilebased approach is promising and holds high pote...
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b3-Adrenoceptor agonists have recently been introduced for the treatment of overactive urinary bladder syndrome. Their target, the b3-adrenoceptor, was discovered much later than b1and b2-adrenoceptors and exhibits unique properties which make extrapolation of findings from the other two subtypes difficult and the b3-adrenoceptor a less-understood subtype. This article discusses three aspects o...
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New evidence of dioxin's ability to cause cancer in humans has come to light[1] just as environmental justice activists across the U.S. are planning a major campaign to attack dioxin at its sources. The campaign is holding a 3-day strategy session in Baton Rouge, Louisiana, March 1517. (All citizen activists are welcome; to register, phone Jim Warren in North Carolina: (919) 774-9566; THE LAST ...
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ژورنال
عنوان ژورنال: Pediatric Critical Care Medicine
سال: 2018
ISSN: 1529-7535
DOI: 10.1097/01.pcc.0000537936.28186.7b